Article
Automated In Vivo Phenotypic Screening Platform for Identifying Factors that Affect Cell Regeneration Kinetics.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2025
Ceisel Anneliese, Emmerich Kevin, McNamara George, Graziano Gianna, Banerjee Shreya, Reibman Barak, Saxena Meera T, Mumm Jeff S
Abstract excerpt
Various strategies for replacing retinal neurons lost in degenerative diseases are under investigation, including stimulating the endogenous regenerative capacity of Müller Glia (MG) as injury-inducible retinal stem cells. Inherently regenerative species, such as zebrafish, have provided key insights into mechanisms regulating MG dedifferentiation to a stem-like state and the proliferation of MG and MG-derived...
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