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Article

Comparative genomic and immunopathologic analysis of lung adenocarcinomas with and without cytology-proven malignant pleural effusions.

Cancer cytopathology - 1 Dec 2024

Pineda Cristiana M, Majid Adnan, Costa Daniel B, VanderLaan Paul A

Abstract excerpt

BACKGROUND: Lung cancer complicated by malignant pleural effusions (MPEs) is associated with significantly increased morbidity and mortality, yet the mechanisms of MPE development remain poorly understood. This study sought to elucidate whether there were specific genomic alterations and/or immunologic biomarkers associated with the presence of MPEs. METHODS: Analysis of comprehensive genomic and immunologic...

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Source

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Identifiers

PMID: 39207725
DOI: 10.1002/cncy.22900
PMCID: PMC12101080

Genes

STK11
EGFR
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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