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Article

The role of cancer-associated fibroblasts in tumorigenesis of gastric cancer

16 Oct 2022

Abstract excerpt

Despite advances in anticancer therapy, the prognosis of gastric cancer (GC) remains unsatisfactory. Research in recent years has shown that the malignant behavior of cancer is not only attributable to tumor cells but is partly mediated by the activity of the cancer stroma and controlled by various molecular networks in the tumor microenvironment (TME). Cancer-associated fibroblasts (CAFs) are one of the most...

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PMID: 36244987
DOI: 10.1038/s41419-022-05320-8

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