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Article

Improvement of Saccharomyces cerevisiae strain tolerance to vanillin through heavy ion radiation combined with adaptive laboratory evolution.

Journal of biotechnology - 10 Nov 2024

Jia Chenglin, Chai Ran, Zhang Miaomiao, Guo Xiaopeng, Zhou Xiang, Ding Nan, Lei Cairong, Dong Ziyi, Zhao Jingru, Ren Haiwei, Lu Dong

Abstract excerpt

Vanillin is an inhibitor of lignocellulose hydrolysate, which can reduce the ability of Saccharomyces cerevisiae to utilize lignocellulose, which is an important factor limiting the development of the ethanol fermentation industry. In this study, mutants of vanillin-tolerant yeast named H6, H7, X3, and X8 were bred by heavy ion irradiation (HIR) combined with adaptive laboratory evolution (ALE). Phenotypic tests...

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PMID: 39197754
DOI: 10.1016/j.jbiotec.2024.08.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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