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Article

Genetically predicted triglyceride levels and endometriosis risk: Mendelian randomization with exploratory multi-omics analyses.

PloS one - 1 Jan 2026

Li Yonghong, He Jianan, Zhang Yuanqing, Yang Min, Jia Zhimao, Fan Yidan, Liu Shuyun, Qi Mengsha

Abstract excerpt

This study explored the genetic evidence linking triglyceride-related pathways and lipid-lowering drug targets with endometriosis risk and investigated the genetic association between TG levels and EM. Using genome-wide association study (GWAS) data, a two-sample Mendelian randomization (MR) analysis was conducted, estimating the association between genetically predicted TG levels and EM risk (OR = 1.1853, 95%...

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Share to Endometriosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mendelian Randomization Analysis

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 42594068
DOI: 10.1371/journal.pone.0356100
PMCID: PMC13472424

Genes

TG
APOA1
BACE1
SCN3A
ESR1
ITGAV
PPARA
SLC9A1
TNF
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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