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Correlation of blood cell counts with mutant subtypes and impact prognosis in acute myeloid leukemia patients with FLT3 mutations.

Hematology (Amsterdam, Netherlands) - 1 Dec 2023

Chen Yang, Xie Yanyan, Fang Yu, Hong Ming, Shi Jinning, Qian Sixuan

Abstract excerpt

OBJECTIVES: Acute myeloid leukemia (AML) often presents with abnormal blood cell counts and gene mutations at diagnosis. But, the correlation between blood cell counts and gene mutations and the clinical effects on AML is unclear. METHODS: 279 AML patients with FMS-like tyrosine kinase 3(FLT3) mutations were selected. Patients with FLT3 mutations were counted by PCR amplification products direct sequencing and...

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PMID: 36738279
DOI: 10.1080/16078454.2023.2172296

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