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Article

Clinical usefulness of NGS multi-gene panel testing in hereditary cancer analysis

1 Feb 2023

Abstract excerpt

Introduction: A considerable number of families with pedigrees suggestive of a Mendelian form of Breast Cancer (BC), Ovarian Cancer (OC), or Pancreatic Cancer (PC) do not show detectable BRCA1/2 mutations after genetic testing. The use of multi-gene hereditary cancer panels increases the possibility to identify individuals with cancer predisposing gene variants. Our study was aimed to evaluate the increase in the...

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PMID: 37065479
DOI: 10.3389/fgene.2023.1060504

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