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The tetraspanin web revisited by super-resolution microscopy

17 Jul 2015

Abstract excerpt

The spatial organization of membrane proteins in the plasma membrane is critical for signal transduction, cell communication and membrane trafficking. Tetraspanins organize functional higher-order protein complexes called 'tetraspanin-enriched microdomains (TEMs)' via interactions with partner molecules and other tetraspanins. Still, the nanoscale organization of TEMs in native plasma membranes has not been...

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PMID: 26183063
DOI: 10.1038/srep12201

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