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Tetraspanins at a glance

1 Jan 2014

Abstract excerpt

Tetraspanins are a family of proteins with four transmembrane domains that play a role in many aspects of cell biology and physiology; they are also used by several pathogens for infection and regulate cancer progression. Many tetraspanins associate specifically and directly with a limited number of proteins, and also with other tetraspanins, thereby generating a hierarchical network of interactions. Through...

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PMID: 25128561
DOI: 10.1242/jcs.154906

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