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Article

HPV-16 E6 mutation and viral integration related host DNA methylation implicate the development and progression of cervical cancer.

Infectious diseases (London, England) - 1 Jan 2025

Huang Chenjun, Xiao Xiao, Ai Wenchao, Huang Honglian, Xu Xuewen, Zhou Xiaoyan, Wang Mengmeng, Zhang Zeyu, Wang Ying, Chunfang Gao

Abstract excerpt

BACKGROUND: HPV-16 infection and viral-host integration are the most important risk factors for cervical cancer (CC). The aim of this study is to develop a new molecular strategy integrated both the viral and host genome variations identifying and monitoring CC. METHOD: A total of 312 methylation and 538 RNA-seq datasets were collected from public databases to identify differentially methylated and expressed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Oncogene Proteins, Viral

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Source

Identifiers

PMID: 39154329
DOI: 10.1080/23744235.2024.2391538

Genes

ZNF671
ASTN1
DLX1
ITGA4
RXFP3
SOX17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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