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Article

Expression of EMT inducers integrin-linked kinase (ILK) and ZEB1 in phyllodes breast tumors is associated with aggressive phenotype.

Histology and histopathology - 1 Sept 2018

Akrida Ioanna, Nikou Sofia, Gyftopoulos Konstantinos, Argentou Marianna, Kounelis Sofia, Zolota Vassiliki, Bravou Vasiliki, Papadaki Helen

Abstract excerpt

Phyllodes tumors (PTs) of the breast constitute an uncommon group of mammary ﬁbroepithelial lesions with ambiguous biologic behavior. Recent evidence suggests that epithelial mesenchymal transition (EMT), a driving force of cancer progression is implicated in PTs pathogenesis. Integrin-linked kinase (ILK), a focal adhesion kinase, has been implicated in cancer and EMT and represents a novel cancer therapeutic...

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Identifiers

PMID: 29608014
DOI: 10.14670/HH-11-987

Genes

ILK
ZEB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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Expression of EMT inducers integrin-linked kinase (ILK) and ZEB1 in phyllodes breast tumors is associated with aggressive phenotype.PMID 29608014Read ↗

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