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Article

RNF43 in cancer: Molecular understanding and clinical significance in immunotherapy.

The journal of gene medicine - 1 Aug 2024

Huo Xingfa, Han Weizhong, Yang Zhen, Lu Yongzhi, Liu Ning, Hou Helei

Abstract excerpt

Identifying biomarkers to predict immune checkpoint inhibitor (ICI) efficacy is warranted. Considering that somatic mutation-derived neoantigens induce strong immune responses, patients with a high tumor mutational burden reportedly tend to respond to ICIs. Therefore, the original function of neoantigenic mutations and their impact on the tumor microenvironment (TME) require attention. RNF43 is a type of RING E3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39146560
DOI: 10.1002/jgm.3729

Genes

RNF43

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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