Article
Inter- and intra-specific pan-genomes of Borrelia burgdorferi sensu lato: genome stability and adaptive radiation.
BMC genomics - 10 Oct 2013
Mongodin Emmanuel F, Casjens Sherwood R, Bruno John F, Xu Yun, Drabek Elliott Franco, Riley David R, Cantarel Brandi L, Pagan Pedro E, Hernandez Yozen A, Vargas Levy C, Dunn John J, Schutzer Steven E, Fraser Claire M, Qiu Wei-Gang, Luft Benjamin J
Abstract excerpt
BACKGROUND: Lyme disease is caused by spirochete bacteria from the Borrelia burgdorferi sensu lato (B. burgdorferi s.l.) species complex. To reconstruct the evolution of B. burgdorferi s.l. and identify the genomic basis of its human virulence, we compared the genomes of 23 B. burgdorferi s.l. isolates from Europe and the United States, including B. burgdorferi sensu stricto (B. burgdorferi s.s., 14 isolates), B....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.