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Clinical characteristics and genetic analysis of a case of a patient with familial hereditary breast cancer: a case report.

Journal of medical case reports - 14 Aug 2024

Liu Yuan, Mao Jinglin, Xiang Longquan, Zhang Xiangyu, Qu Zhen

Abstract excerpt

BACKGROUND: Breast cancer has emerged as the foremost cause of female mortality worldwide, with triple negative breast cancer accounting for approximately 10-15% of all breast cancer cases. The triple negative breast cancer family has obvious familial heritability, but no potential pathogenic variation was found in BRCA1/2. CASE PRESENTATION: The patient was a 56-year-old woman of Han ethnicity. The clinical...

Topics

Humans
Female
Middle Aged
Breast Neoplasms
Triple Negative Breast Neoplasms
Exome Sequencing
Pedigree
Genetic Predisposition to Disease
Mutation
BRCA1 Protein
Genetic Testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39138583
DOI: 10.1186/s13256-024-04685-y
PMCID: PMC11323601

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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