Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Macular structural integrity estimates are associated with Parkinson's disease genetic risk.

Acta neuropathologica communications - 13 Aug 2024

Diaz-Torres Santiago, Lee Samantha Sze-Yee, Ogonowski Natalia S, Mackey David A, MacGregor Stuart, Gharahkhani Puya, Renteria Miguel E

Abstract excerpt

BACKGROUND: Optical coherence tomography (OCT) is a non-invasive technique to measure retinal layer thickness, providing insights into retinal ganglion cell integrity. Studies have shown reduced retinal nerve fibre layer (RNFL) and ganglion cell inner plexiform layer (GCIPL) thickness in Parkinson's disease (PD) patients. However, it is unclear if there is a common genetic overlap between the macula and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Predisposition to Disease
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Macula Lutea

Share to Multifactorial Inheritance

Share to Parkinson Disease

Share to Retinal Ganglion Cells

Share to Tomography, Optical Coherence

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 39135092
DOI: 10.1186/s40478-024-01841-9
PMCID: PMC11320880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Macular structural integrity estimates are associated with Parkinson's disease genetic risk.PMID 39135092Read ↗

Sub-cellular level resolution of common genetic variation in the photoreceptor layer identifies continuum between rare disease and common variation.Semantic proximity Read ↗

Sub-cellular level resolution of common genetic variation in the photoreceptor layer identifies continuum between rare disease and common variationSemantic proximity Read ↗

Genetic Analysis of Retinal Cell Types in Neuropsychiatric DisordersSemantic proximity Read ↗

Genetic analysis of retinal cell types reveals synaptic pathology in schizophreniaSemantic proximity Read ↗

Disentangling the genetic overlap and causal relationships between primary open-angle glaucoma, brain morphology and four major neurodegenerative disordersSemantic proximity Read ↗

Genetic Risk Assessment of Degenerative Eye Disease (GRADE): Design of a prospective assessment of polygenic risk scores to predict diagnosis of glaucoma and age-related macular degeneration.Semantic proximity Read ↗

Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images.Semantic proximity Read ↗

Neuroanatomical correlates of polygenic risk for Parkinson’s DiseaseSemantic proximity Read ↗

Genetic variation affects morphological retinal phenotypes extracted from UK Biobank Optical Coherence Tomography imagesSemantic proximity Read ↗

Association between polygenic risk for schizophrenia and retinal morphology: A cross-sectional analysis of the United Kingdom Biobank.Semantic proximity Read ↗

Insights into human health from phenome- and genome-wide analyses of UK Biobank retinal optical coherence tomography phenotypesSemantic proximity Read ↗

Fine-mapping of Parkinson's disease susceptibility loci identifies putative causal variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.