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Clinical significance of macrophage phenotypes in cardiovascular disease

21 Nov 2014

Abstract excerpt

The emerging understanding of macrophage subsets and their functions in the atherosclerotic plaque has led to the consensus that M1 macrophages are pro-atherogenic while M2 macrophages may promote plaque stability, primarily though their tissue repair and anti-inflammatory properties. As such, modulating macrophage function to promote plaque stability is an exciting therapeutic prospect. This review will outline...

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PMID: 25635207
DOI: 10.1186/s40169-014-0042-1

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