Article
Imputation strategies for low-coverage whole-genome sequencing data and their effects on genomic prediction and genome-wide association studies in pigs.
Animal : an international journal of animal bioscience - 1 Sept 2024
Wang X Q, Wang L G, Shi L Y, Tian J J, Li M Y, Wang L X, Zhao F P
Abstract excerpt
The uncertainty resulting from missing genotypes in low-coverage whole-genome sequencing (LCWGS) data complicates genotype imputation. The aim of this study is to find out an optimal strategy for accurately imputing LCWGS data and assess its effectiveness for genomic prediction (GP) and genome-wide association study (GWAS) on economically important traits of Large White pigs. The LCWGS data of 1 423 Large White...
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