Article
The construction of a haplotype reference panel using extremely low coverage whole genome sequences and its application in genome-wide association studies and genomic prediction in Duroc pigs.
Genomics - 1 Jan 2022
Zhang Zhe, Ma Peipei, Zhang Zhenyang, Wang Zhen, Wang Qishan, Pan Yuchun
Abstract excerpt
Extremely low coverage whole genome sequencing (lcWGS) is an economical technique to obtain high-density single nucleotide polymorphisms (SNPs). Here, we explored the feasibility of constructing a haplotype reference panel (lcHRP) using lcWGS and evaluated the effects of lcHRP through a genome-wide association study (GWAS) and genomic prediction in pigs. A total of 297 and 974 Duroc pigs were genotyped using...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.