Article
PHARP: a pig haplotype reference panel for genotype imputation.
Scientific reports - 25 Jul 2022
Wang Zhen, Zhang Zhenyang, Chen Zitao, Sun Jiabao, Cao Caiyun, Wu Fen, Xu Zhong, Zhao Wei, Sun Hao, Guo Longyu, Zhang Zhe, Wang Qishan, Pan Yuchun
Abstract excerpt
Pigs not only function as a major meat source worldwide but also are commonly used as an animal model for studying human complex traits. A large haplotype reference panel has been used to facilitate efficient phasing and imputation of relatively sparse genome-wide microarray chips and low-coverage sequencing data. Using the imputed genotypes in the downstream analysis, such as GWASs, TWASs, eQTL mapping and...
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