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Article

The clinical implications of BCOR mutations in a large cohort of acute myeloid leukemia patients: a 5-year single-center retrospective study.

Leukemia & lymphoma - 1 Dec 2024

Hu Deyuan, Shen Kai, Guo YuSha, Bao Xie Bing, Dong Ningzheng, Chen Suning

Abstract excerpt

To elucidate the effect of BCOR mutation (BCORmut) on clinical outcomes, we included a total of 899 consecutive AML patients in a single-center during July 2016 to December 2021. Fifty cases (5.6%) had BCOR mutations, which co-occurred with mutations of RUNX1, DNMT3A, IDH2, BCORL1, STAG2, SF3B1 and U2AF1, but were exclusive with KIT and CEBPA mutations. BCORmut was also found to be exclusive with...

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Source

Identifiers

PMID: 39126311
DOI: 10.1080/10428194.2024.2387730

Genes

BCOR
BCORL1
DNMT3A
ELN
IDH2
KIT
RUNX1
SF3B1
STAG2
U2AF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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