Features and impacts on the prognosis of gene mutations in patients with acute myeloid leukemia.

Abstract excerpt

To explore features and impacts on the prognosis of common gene mutations in acute myeloid leukemia (AML), we assessed mutation status as well as variant allele frequency (VAF) of 24 genes in 81 AML patients by next-generation sequencing (NGS) technology. Eighty-six percentages of patients showed at least one mutation. Mutation in BCOR was associated with lower complete remission (CR) rate, whereas double...

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