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Study of Interleukin 28B rs12979860 and rs8099917 Polymorphisms and T-helper 1 Response in Hepatitis C Virus Patients.

The Egyptian journal of immunology - 1 Jun 2015

Ea Rashwan, Aa Ghazy, Ag El-Sheredy, Ma Abdelnaby

Abstract excerpt

HCV infection is a serious public health problem and a leading cause of chronic liver disease. It affects nearly 3% of the world's population with an associated high mortality. Egypt has the highest prevalence of HCV infection in the world (estimated at >10%). Peg-IFN-α and RBV are the most widely used therapy for HCV. Unfortunately, the rate of SVR is around 50%. In addition, it is expensive and associated with...

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PMID: 28502145

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