The Synergistic Effect of Fluvastatin and IFN-λ on Peripheral Blood Mononuclear Cells of Chronic Hepatitis C Virus (HCV) Patients with IL-28B rs12979860 CC Genotype.

doi:10.18502/ijaai.v18i5.1923

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The Synergistic Effect of Fluvastatin and IFN-λ on Peripheral Blood Mononuclear Cells of Chronic Hepatitis C Virus (HCV) Patients with IL-28B rs12979860 CC Genotype.

Iranian journal of allergy, asthma, and immunology - 23 Oct 2019

Farzanegan Gharabolagh Amin, Bamdad Taravat, Hedayati Mehdi, Dehghan Manshadi Seyed Ali

Abstract excerpt

There is a relationship between the life cycle of the hepatitis C virus (HCV) and the synthesis and hemostasis of lipids as well as lipid metabolism and interferon (IFN) regulatory system. This study was aimed to examine the effect of fluvastatin and IFN-ƛ in the expression of mediators involved in lipid metabolism and HCV proliferation in patients with rs12979860 CC polymorphism. Thirteen patients with HCV and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Synergism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antiviral Agents

Share to ATP Binding Cassette Transporter 1

Share to Cells, Cultured

Share to Hepacivirus

Share to Hepatitis C, Chronic

Share to Interferons

Share to Leukocytes, Mononuclear

Source

Open in PubMed

Identifiers

PMID: 32245297
DOI: 10.18502/ijaai.v18i5.1923

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Synergistic Effect of Fluvastatin and IFN-λ on Peripheral Blood Mononuclear Cells of Chronic Hepatitis C Virus (HCV) Patients with IL-28B rs12979860 CC Genotype.PMID 32245297Read ↗

Hepatitis C virus infection alters lipid metabolism depending on IL28B polymorphism and viral genotype and modulates gene expression in vivo and in vitro.Semantic proximity Read ↗

Modulation of host lipid metabolism by hepatitis C virus: Role of new therapies.Semantic proximity Read ↗

An open-label randomized controlled study of pegylated interferon/ribavirin combination therapy for chronic hepatitis C with versus without fluvastatin.Semantic proximity Read ↗

Distinct and overlapping genomic profiles and antiviral effects of Interferon‐λ and ‐α on HCV‐infected and noninfected hepatoma cellsSemantic proximity Read ↗

Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease.Semantic proximity Read ↗

Effect of fluvastatin on 24-week telaprevir-based combination therapy for hepatitis C virus genotype 1b-infected chronic hepatitis C.Semantic proximity Read ↗

The cell biology of hepatitis C virus (HCV) lipid addiction: molecular mechanisms and its potential importance in the clinic.Semantic proximity Read ↗

Effects of fatty liver and related factors on the efficacy of combination antiviral therapy in patients with chronic hepatitis C.Semantic proximity Read ↗

Effect of antiviral therapy for HCV on lipid levels.Semantic proximity Read ↗

Hepatitis C virus nonstructural 4B protein modulates sterol regulatory element-binding protein signaling via the AKT pathway.Semantic proximity Read ↗

Cellular Mechanism for Impaired Hepatitis C Virus Clearance by Interferon Associated with IFNL3 Gene Polymorphisms Relates to Intrahepatic Interferon-λ Expression.Semantic proximity Read ↗

Reliance of Host Cholesterol Metabolic Pathways for the Life Cycle of Hepatitis C VirusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.