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Article

Proteomic Characterization of Middle Ear Fluid Confirms Neutrophil Extracellular Traps as a Predominant Innate Immune Response in Chronic Otitis Media

14 Apr 2016

Abstract excerpt

BACKGROUND: Chronic Otitis Media (COM) is characterized by middle ear effusion (MEE) and conductive hearing loss. MEE reflect mucus hypersecretion, but global proteomic profiling of the mucosal components are limited. OBJECTIVE: This study aimed at characterizing the proteome of MEEs from children with COM with the goal of elucidating important innate immune responses. METHOD: MEEs were collected from children (n...

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Share to Ear Surgery and Otitis Media
Share to Hearing, Cochlea, Tinnitus, Genetics
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PMID: 27078692
DOI: 10.1371/journal.pone.0152865

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