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Article

Single gene mutations and prognosis in limited-stage follicular lymphoma treated with radiation therapy.

British journal of haematology - 1 Nov 2024

Hershenfeld Samantha A, Tobin Josuha W D, Shelton Victoria, Calvente Lourdes, Lajkosz Katherine, Liu Ting, Brodtkorb Marianne, d'Amore Francesco Annibale, Ludvigsen Maja, Baetz Tara, LeBrun David, Johnson Nathalie, Crump Michael, Hong Michael, Kuruvilla John, Tremblay-LeMay Rosemarie, MacManus Michael, Tsang Richard, Hodgson David C, Gandhi Maher K, Kridel Robert

Abstract excerpt

Radiotherapy is routinely used for management of limited-stage follicular lymphoma (FL), yet half of patients ultimately relapse. We hypothesized that the presence of specific gene mutations may predict outcomes. We performed targeted sequencing of a 69-gene panel in 117 limited-stage FL patients treated with radiotherapy and identified recurrently mutated genes. CREBBP was most frequently mutated, and mutated...

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Identifiers

PMID: 39112220
DOI: 10.1111/bjh.19698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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