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Article

Involvement of IL17A and IL17RA variants in interleukin-17A levels and disease activity in ulcerative colitis.

Cytokine - 1 Oct 2024

Paula Sanchez Zanotti Mariana, Cataldi de Alcântara Camila, Junko Inoue Cláudia, Piantoni Gonçalves Beatriz, Rabello Espinosa Beatriz, Luiz Cândido de Souza Cassela Pedro, Lerner Trigo Guilherme, Mendes Ahrens Tainah, Alysson Batisti Lozovoy Marcell, Eduardo Coral de Oliveira Carlos, Maria Vissoci Reiche Edna, Name Colado Simão Andréa

Abstract excerpt

Ulcerative colitis (UC) is characterized by chronic inflammation of the large intestine with involvement of Th17 cells and interleukin (IL)-17A. The role of IL17A and IL17A receptor (IL17RA) variants in pathophysiology of UC still remains inconclusive. The aim was to evaluate the association between IL17A and IL17RA variants with susceptibility, IL-17A plasma levels, and endoscopic activity in UC. The study...

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Source

Identifiers

PMID: 39111114
DOI: 10.1016/j.cyto.2024.156716

Genes

IL17A
IL17RA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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