Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The influence of polymorphisms of interleukin-17A and interleukin-17F genes on the susceptibility to ulcerative colitis.

Journal of clinical immunology - 1 Jan 2008

Arisawa Tomiyasu, Tahara Tomomitsu, Shibata Tomoyuki, Nagasaka Mitsuo, Nakamura Masakatsu, Kamiya Yoshio, Fujita Hiroshi, Nakamura Masahiko, Yoshioka Daisuke, Arima Yuko, Okubo Masaaki, Hirata Ichiro, Nakano Hiroshi

Abstract excerpt

We investigated the association between ulcerative colitis (UC) and polymorphisms of IL-17A (rs2275913, G-197A) and IL-17F (rs763780, 7488T/C) genes. We employed the multiplex PCR-SSCP method to detect gene polymorphisms. Both the numbers of -197A (IL-17A) and 7488T (IL-17F) alleles were significantly correlated to the development of UC. The frequencies of -197A/A and 7488T/T genotypes in the UC group were...

Topics

Adult
Aged
Alleles
Colitis, Ulcerative
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Frequency

Genetic Predisposition to Disease

Genotype

Humans

Interleukin-17

Male

Middle Aged

Polymorphism, Genetic

Source

Identifiers

PMID: 17828618
DOI: 10.1007/s10875-007-9125-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-17828618-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The influence of polymorphisms of interleukin-17A and interleukin-17F genes on the susceptibility to ulcerative colitis.PMID 17828618Read ↗

Influence of IL17A polymorphisms (rs2275913 and rs3748067) on the susceptibility to ulcerative colitis.Semantic proximity Read ↗

Genetic polymorphisms of interleukin 17A and interleukin 17F and their association with inflammatory bowel disease in a Chinese Han population.Semantic proximity Read ↗

Involvement of IL17A and IL17RA variants in interleukin-17A levels and disease activity in ulcerative colitis.Semantic proximity Read ↗

Interleukin-17 SNPs and serum levels increase ulcerative colitis risk: a meta-analysis.Semantic proximity Read ↗

Association of interleukin-17F 7488 single nucleotide polymorphism and inflammatory bowel disease in the Chinese population.Semantic proximity Read ↗

Genetic polymorphism of interleukin-17A and -17F genes in gastric carcinogenesis.Semantic proximity Read ↗

Involvement of IL17A and IL17RA variants in interleukin-17A levels and disease activity in ulcerative colitisSemantic proximity Read ↗

Meta-Analysis of Risk Association Between Interleukin-17A and F Gene Polymorphisms and Inflammatory Diseases.Semantic proximity Read ↗

Association of genetic polymorphisms in IL17A and IL17F with gastro-duodenal diseases.Semantic proximity Read ↗

Genetic polymorphisms in the IL-18 gene and ulcerative colitis risk: a meta-analysis.Semantic proximity Read ↗

IL-17A and IL-17F genes variants and susceptibility to childhood asthma in Tunisia.Semantic proximity Read ↗

The Influence of Polymorphisms of Interleukin-17A and -17F Genes on Susceptibility and Activity of Rheumatoid Arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.