Article
Interleukin-17 serum levels and TLR4 polymorphisms in ulcerative colitis.
Iranian journal of immunology : IJI - 1 Jun 2013
Mohammadi Mojgan, Zahedi Mohammad Javad, Nikpoor Amin Reza, Baneshi Mohammad Reza, Hayatbakhsh Mohammad Mahdi
Abstract excerpt
BACKGROUND: Inflammatory bowel disease, an autoimmune disease, has two clinical manifestations including Crohn's disease and ulcerative colitis (UC). IL-17 has been the target of intensive research in autoimmune diseases. The influence of Toll like receptor 4 (TLR-4) gene polymorphisms on IL-17 production has also been revealed in UC patients and tissue inflammation in mice. OBJECTIVES: To investigate the...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Colitis, Ulcerative
- DNA Mutational Analysis
- Female
- Genetic Association Studies
- Genetic Predisposition to Disease
- Hemoglobins
- Humans
- Interleukin-17
- Iran
- Male
- Middle Aged
- Polymorphism, Genetic
- Toll-Like Receptor 4
- Young Adult
