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Article

Causal relationships between gut microbiome and aplastic anemia: a Mendelian randomization analysis.

Hematology (Amsterdam, Netherlands) - 1 Dec 2024

Liu Juan, Wang Xin, Huang Liping, Lin Xinlu, Yin Wei, Chen Mingliang

Abstract excerpt

BACKGROUND: Previous observational studies have hinted at a potential correlation between aplastic anemia (AA) and the gut microbiome. However, the precise nature of this bidirectional causal relationship remains uncertain. METHODS: We conducted a bidirectional two-sample Mendelian randomization (MR) study to investigate the potential causal link between the gut microbiome and AA. Statistical analysis of the gut...

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PMID: 39240224
DOI: 10.1080/16078454.2024.2399421

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