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Article

Causal role of lipid metabolism in pulmonary alveolar proteinosis: an observational and mendelian randomisation study.

Thorax - 18 Jan 2024

Huang Junfeng, Lin Zikai, Lin Jinsheng, Xie Shuojia, Xia Shixin, Chen Gengjia, Zheng Ziwen, Xu Zhe, Liu Fangcheng, Wu Hongkai, Li Shiyue

Abstract excerpt

BACKGROUND: Pulmonary alveolar proteinosis (PAP) is a rare interstitial lung disease characterised by the accumulation of lipoprotein material in the alveoli. Although dyslipidaemia is a prominet feature, the causal effect of lipid traits on PAP remains unclear. This study aimed to explore the role of lipid traits in PAP and evaluate the potential of lipid-lowering drug targets in PAP. METHODS: Clinical outcomes,...

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Source

Identifiers

PMID: 38124156
DOI: 10.1136/thorax-2023-220789

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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