Article
RNA-DNA differences in variant calls from cattle tissues result in erroneous eQTLs.
BMC genomics - 1 Aug 2024
Leonard Alexander S, Mapel Xena M, Pausch Hubert
Abstract excerpt
BACKGROUND: Association testing between molecular phenotypes and genomic variants can help to understand how genotype affects phenotype. RNA sequencing provides access to molecular phenotypes such as gene expression and alternative splicing while DNA sequencing or microarray genotyping are the prevailing options to obtain genomic variants. RESULTS: We genotype variants for 74 male Braunvieh cattle from both DNA...
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