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Article

Developmental analysis of Spalt function in the Drosophila prothoracic gland.

Development (Cambridge, England) - 15 Aug 2024

Ostalé Cristina M, Pulido Diego, Vega-Cuesta Patricia, López-Varea Ana, de Celis Jose F

Abstract excerpt

The Spalt transcriptional regulators participate in a variety of cell fate specification processes during development, regulating transcription through interactions with DNA AT-rich regions. Spalt proteins also bind to heterochromatic regions, and some of their effects require interactions with the NuRD chromatin remodeling and deacetylase complex. Most of the biological roles of Spalt proteins have been...

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PMID: 39087588
DOI: 10.1242/dev.202751
PMCID: PMC11385645

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