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Increased levels of circulating cell-free DNA in COVID-19 patients with respiratory failure

29 Jul 2024

Abstract excerpt

Cell-free DNA (cfDNA) is released from injured cells and aggravates inflammation. Patients with coronavirus disease (COVID-19) often develop pneumonia and respiratory failure, and require oxygen therapy (OT), including mechanical ventilation (MV). It remains unclear whether cfDNA predicts the risk of receiving OT or MV in COVID-19 patients. Therefore, we hypothesized that circulating cfDNA levels could reflect...

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PMID: 39075117
DOI: 10.1038/s41598-024-68433-4

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