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Circulating mitochondrial DNA is an early indicator of severe illness and mortality from COVID-19

14 Jan 2021

Abstract excerpt

BackgroundMitochondrial DNA (MT-DNA) are intrinsically inflammatory nucleic acids released by damaged solid organs. Whether circulating cell-free MT-DNA quantitation could be used to predict the risk of poor COVID-19 outcomes remains undetermined.MethodsWe measured circulating MT-DNA levels in prospectively collected, cell-free plasma samples from 97 subjects with COVID-19 at hospital presentation. Our primary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33444289
DOI: 10.1172/jci.insight.143299

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