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Cell-free DNA maps COVID-19 tissue injury and risk of death and can cause tissue injury

2 Mar 2021

Abstract excerpt

INTRODUCTIONThe clinical course of coronavirus 2019 (COVID-19) is heterogeneous, ranging from mild to severe multiorgan failure and death. In this study, we analyzed cell-free DNA (cfDNA) as a biomarker of injury to define the sources of tissue injury that contribute to such different trajectories.METHODSWe conducted a multicenter prospective cohort study to enroll patients with COVID-19 and collect plasma...

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Identifiers

PMID: 33651717
DOI: 10.1172/jci.insight.147610

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