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Environmental Exposure, Obesity, and Parkinson’s Disease: Lessons from Fat and Old Worms

25 Aug 2010

Abstract excerpt

BACKGROUND: A common link has been exposed, namely, that metal exposure plays a role in obesity and in Parkinson's disease (PD). This link may help to elucidate mechanisms of neurotoxicity. OBJECTIVE: We reviewed the utility of the nematode, Caenorhabditis elegans, as a model organism to study neurodegeneration in obesity and Parkinson's disease (PD), with an emphasis on the neurotransmitter, dopamine (DA). DATA...

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PMID: 20797931
DOI: 10.1289/ehp.1002522

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