Article
β-N-methylamino-L-alanine production, photosynthesis and transcriptional expression in a possible mutation strain and a wild strain of Thalassiosira minima.
Journal of hazardous materials - 15 Sept 2024
Zheng Xianyao, Li Aifeng, Qiu Jiangbing, Yan Guowang, Ji Ying, Wang Guixiang
Abstract excerpt
The neurotoxin β-N-methylamino-L-alanine (BMAA) produced by marine diatoms has been implicated as an important environmental trigger of neurodegenerative diseases in humans. However, the biosynthesis mechanism of BMAA in marine diatoms is still unknown. In the present study, the strain of diatom Thalassiosira minima almost lost the biosynthesis ability for BMAA after a long-term subculture in our laboratory. The...
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