Article
Intramuscular administration of fractalkine modulates mitochondrial properties and promotes fast glycolytic phenotype.
BioFactors (Oxford, England) - 1 Jan 2000
Swalsingh Gourabamani, Pani Punyadhara, Senapati Unmod, Sahu Bijayashree, Pani Sunil, Pati Benudhara, Rout Subhasmita, Bal Naresh C
Abstract excerpt
A newly categorized myokine called fractalkine (CX3CL1) has been associated with divergent conditions such as obesity, tissue inflammation, and exercise. CX3CL1 works through specific membrane-bound receptors (CX3CR1) found in various tissues including skeletal muscles. Studies indicate CX3CL1 induces muscles to uptake energy substrates thereby improving glucose utilization and countering diabetes. Here, we...
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