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DNA methylome analysis reveals epigenetic alteration of complement genes in advanced metabolic dysfunction-associated steatotic liver disease

25 Jul 2024

Abstract excerpt

BACKGROUND/AIMS: Blocking the complement system is a promising strategy to impede the progression of metabolic dysfunction-associated steatotic liver disease (MASLD). However, the interplay between complement and MASLD remains to be elucidated. This comprehensive approach aimed to investigate the potential association between complement dysregulation and the histological severity of MASLD. METHODS: Liver biopsy...

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PMID: 39048522
DOI: 10.3350/cmh.2024.0229

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