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Integrative transcriptomic and genomic analyses unveil the IFI16 variants and expression as MASLD progression markers

20 Feb 2024

Abstract excerpt

BACKGROUND AND AIMS: Metabolic dysfunction-associated steatotic liver disease (MASLD) encompasses a broad and continuous spectrum of liver diseases ranging from fatty liver to steatohepatitis. The intricate interactions of genetic, epigenetic, and environmental factors in the development and progression of MASLD remain elusive. Here, we aimed to achieve an integrative understanding of the genomic and...

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PMID: 38385945
DOI: 10.1097/hep.0000000000000805

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