Article
Association analysis of indel variants and gene expression identifies MDM4 as a novel locus for skeletal muscle hypertrophy and power athlete status.
Experimental physiology - 1 Nov 2025
Kazan Hasan H, Kasakolu Anıl, Koncagul Seyrani, Ergun Mehmet A, John George, Sultanov Rinat I, Zhelankin Andrey V, Semenova Ekaterina A, Yusupov Rinat A, Kulemin Nikolay A, Larin Andrey K, Generozov Edward V, Bulgay Celal, Ahmetov Ildus I
Abstract excerpt
Insertions and deletions (indels) are the second most common type of variation in the human genome. However, limited data on their associations with exercise-related phenotypes have been documented. The aim of the present study was to examine the association between 18,370 indel variants and power athlete status, followed by additional studies in 357,246 individuals. In the discovery phase, the D allele of the...
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