Article
Identification and prioritization of NUAK1 and PPP1CC as positional candidate loci for skeletal muscle strength phenotypes.
Physiological genomics - 8 Sept 2011
Windelinckx An, De Mars Gunther, Huygens Wim, Peeters Maarten W, Vincent Barbara, Wijmenga Cisca, Lambrechts Diether, Aerssens Jeroen, Vlietinck Robert, Beunen Gaston, Thomis Martine A I
Abstract excerpt
Muscle strength is an important determinant in elite sports performance as well as in the activities of daily living. Muscle metabolism also plays a role in the genesis, and therefore prevention, of common pathological conditions and chronic diseases. Even though heritability estimates between 31 and 78% suggest a significant genetic component in muscle strength, only a limited number of genes influencing muscle...
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