p53 Immunohistochemistry Defines a Subset of Human Papillomavirus-Independent Penile Squamous Cell Carcinomas With Adverse Prognosis.

doi:10.1097/PAS.0000000000002291

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Article

p53 Immunohistochemistry Defines a Subset of Human Papillomavirus-Independent Penile Squamous Cell Carcinomas With Adverse Prognosis.

The American journal of surgical pathology - 1 Nov 2024

Trias Isabel, Algaba Ferran, de Torres Inés, Saco Adela, Marimon Lorena, Peñuelas Núria, Diez-Ahijado Laia, Sisuashvili Lia, Darecka Katarzyna, Morató Alba, Del Pino Marta, Ferrándiz-Pulido Carla, Ribal María José, Ajami Tarek, Corral Juan Manuel, Gaya Josep Maria, Reig Oscar, Ordi Oriol, Ribera-Cortada Inmaculada, García-Herrera Adriana, Rakislova Natalia

Abstract excerpt

Penile squamous cell carcinoma (PSCC) is classified into 2 prognostically distinct types: human papillomavirus (HPV)-associated and HPV-independent. However, the impact of p53 status on prognosis remains controversial. We correlated HPV and p53 status with the prognosis of a large series of patients with PSCC. p53 was analyzed according to a recently described immunohistochemical (IHC) pattern-based framework...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39040011
DOI: 10.1097/PAS.0000000000002291
PMCID: PMC11472902

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