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Article

Apolipoprotein ɛ4 Allele and Dental Occlusion Deficiency as Risk Factors for Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2020

Popovac Aleksandra, Mladenović Irena, Krunić Jelena, Trifković Branka, Todorović Ana, Milašin Jelena, Despotović Nebojša, Stančić Ivica

Abstract excerpt

Compromised dentition has been suggested to pose a significant risk factor for dementia. It was mainly investigated through insufficient tooth number, disregarding contact between opposing teeth (dental occlusion). The ɛ4 allele of apolipoprotein (APOE4) is the primary genetic marker for the late onset of Alzheimer's disease (AD). However, APOE4 and dental occlusion have not yet been investigated as possible...

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PMID: 32116259
DOI: 10.3233/JAD-191283

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