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Article

Unraveling the Causal Links Between Immune Traits and Hepatocellular Carcinoma: Insights From a Bi-Directional Mendelian Randomization Study.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 21 Apr 2025

Li Jie, Wang Gechun, Xiang Xiaonan, Wang Jianguo

Abstract excerpt

Background/Aims: Hepatocellular carcinoma (HCC) is significantly influenced by the immune system, which plays a key role in its development, progression, treatment, and prognosis. While observational studies have revealed correlations between circulating immune traits and HCC, their genetic basis and causal links remain unclear. This study aims to investigate the genetic associations and bidirectional causal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40636979
DOI: 10.5152/tjg.2025.24558
PMCID: PMC12257684

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