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Article

Kdm4d mutant mice show impaired sperm motility and subfertility.

The Journal of reproduction and development - 1 Oct 2024

Xu Zhuoran, Fujimoto Yuka, Sakamoto Mizuki, Ito Daiyu, Ikawa Masahito, Ishiuchi Takashi

Abstract excerpt

Regulation of gene expression through histone modifications underlies cell homeostasis and differentiation. Kdm4d and Kdm4dl exhibit a high degree of similarity and demethylate H3K9me3. However, the physiological functions of these proteins remain unclear. In this study, we generated Kdm4dl mutant mice and found that Kdm4dl was dispensable for mouse development. However, through the generation of Kdm4d mutant...

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Share to Histones
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Share to Jumonji Domain-Containing Histone Demethylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39034148
DOI: 10.1262/jrd.2024-039
PMCID: PMC11461516

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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