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Article

Functional metagenomic analysis reveals potential inflammatory triggers associated with genetic risk for autoimmune disease.

Journal of autoimmunity - 1 Sept 2024

Berryman Meghan A, Ilonen Jorma, Triplett Eric W, Ludvigsson Johnny

Abstract excerpt

To assess functional differences between the microbiomes of individuals with autoimmune risk-associated human leukocyte antigen (HLA) genetics and autoimmune protection-associated HLA, we performed a metagenomic analysis of stool samples from 72 infants in the All Babies in Southeast Sweden general-population cohort and assessed haplotype-peptide binding affinities. Infants with risk-associated HLA DR3-DQ2.5 and...

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Identifiers

PMID: 39033688
DOI: 10.1016/j.jaut.2024.103290

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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