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Predicting Infertility: How Genetic Variants in Oocyte Spindle Genes Affect Egg Quality.

Advances in anatomy, embryology, and cell biology - 1 Jan 2024

Biswas Leelabati, Schindler Karen

Abstract excerpt

Successful reproduction relies on the union of a single chromosomally normal egg and sperm. Chromosomally normal eggs develop from precursor cells, called oocytes, that have undergone accurate chromosome segregation. The process of chromosome segregation is governed by the oocyte spindle, a unique cytoskeletal machine that splits chromatin content of the meiotically dividing oocyte. The oocyte spindle develops...

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Genetic Variation
Infertility, Female
Meiosis
Oocytes
Spindle Apparatus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39030352
DOI: 10.1007/978-3-031-55163-5_1

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