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Article

Generation of induced pluripotent stem cell line (XWHNi003-A) from a female with APOE gene mutation.

Stem cell research - 1 Sept 2024

Gong Jin, Li Shaoqi, Sun Wenxian, Wang Pin, Han Xiaodong, Xu Chang, Chen Yufei, Yang Yuting, Luan Heya, Li Ruina, Wen Boye, Lv Sirong, Chen Runqi, Guo Jinxuan, Wei Cuibai

Abstract excerpt

Apolipoprotein E (APOE)is the gene with greatest genetic risk for Alzheimer's disease (AD). We successfully established a human induced pluripotent stem cell(iPSC) line from a woman mutated by APOE gene. The cell line was isolated from this woman's peripheral blood mononuclear cells using a non-integrated Sendai virus, which retained the original genotype, showed a normal karyotype, highly expressed pluripotent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39029293
DOI: 10.1016/j.scr.2024.103501

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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