Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of human induced pluripotent stem cell line (XWHNi004-A) from a male with APOE gene mutation.

Stem cell research - 1 Jun 2024

Wang Pin, Sun Wenxian, Gong Jin, Han Xiaodong, Xu Chang, Chen Yufei, Yang Yuting, Luan Heya, Li Shaoqi, Li Ruina, Wen Boye, Lv Sirong, Chen Runqi, Guo Jinxuan, Wei Cuibai

Abstract excerpt

Genetic polymorphism of apolipoprotein E (APOE) confers differential susceptibility to Alzheimer's disease (AD), and APOE ɛ4 variants is the most powerful risk factor for this disease. Here, we report the generation of a human induced pluripotent stem cell (iPSC) line carrying the APOE ɛ4/ɛ4 genotype from peripheral blood mononuclear cells (PBMCs) isolated from a male with a family history of AD utilizing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins E
Share to Cell Differentiation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line

Share to Induced Pluripotent Stem Cells

Share to Leukocytes, Mononuclear

Share to Mutation

Source

Identifiers

PMID: 38552354
DOI: 10.1016/j.scr.2024.103398

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of human induced pluripotent stem cell line (XWHNi004-A) from a male with APOE gene mutation.PMID 38552354Read ↗

Generation of induced pluripotent stem cell line (XWHNi003-A) from a female with APOE gene mutation.Semantic proximity Read ↗

Establishment of SIAISi021-A, an induced pluripotent stem cell (iPSC) line from a 71-year-old Chinese Han male with Alzheimer's Disease (AD) having two copies of APOE4/4 allele.Semantic proximity Read ↗

Generation and characterization of human induced pluripotent stem cell (hiPSC) lines from an Alzheimer's disease (ASUi003-A) and non-demented control (ASUi004-A) patient homozygous for the Apolipoprotein e4 (APOE4) risk variant.Semantic proximity Read ↗

Generation of induced pluripotent stem cell line (IPTi002-A) from an 87-year old sporadic Alzheimer's disease patient with APOE3 (ε3/ε3) genotype.Semantic proximity Read ↗

Induced pluripotent stem cells derived from one 70-years-old male donor with the APOE-ε4/ε4 alleles.Semantic proximity Read ↗

Generation and characterization of a human induced pluripotent stem cell line (XWHNi001-A) derived from an Alzheimer's disease patient with mutation in the APP gene.Semantic proximity Read ↗

Generation of induced pluripotent stem cell line (IPTi001-A) from a 62-year old sporadic Alzheimer's disease patient with APOE3 (ε3/ε3) genotype.Semantic proximity Read ↗

Integration-free induced pluripotent stem cell line derived from a 62-years-old male donor with APOE-epsilon4/epsilon4 alleles.Semantic proximity Read ↗

Blood-derived integration-free iPS cell line UKBi011-A from a diagnosed male Alzheimer's disease patient with APOE ɛ4/ɛ4 genotype.Semantic proximity Read ↗

Generation of inducible pluripotent stem cell lines from Alzheimer's disease patients with APOE e3/e3 genotype.Semantic proximity Read ↗

Generation of the Human iPSC Line from Spontaneous Late-Onset Alzheimer's Disease Patient with ApoE3/3 Genotype and Sex-, Age-, and ApoE-Matched Healthy Control.Semantic proximity Read ↗

Generation of an induced pluripotent stem cell line (SIAISi009-A) from a 60-year-old Chinese Han female with mild cognitive impairment (MCI) having two copies of APOE4/4 allele.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.